Hey. This is Eddie and I am here to talk about a very powerful
hormone called obestatin prepropeptide, or more commonly known as Ghrelin.
Ghrelin is a hormone that is produced by cells in the lining of the fundus of
the stomach and also epsilon cells of the pancreas. Ghrelin levels rise at
appropriate times to stimulate hunger, and decrease after meals. Ghrelin has a
Neuroendocrine Pattern. Basically, Ghrelin will trigger the neurosecretory
cells in the nervous system by means of the sensory neuron. Then, Ghrelin goes
through the bloodstream and through the body until they react with the
receptors of the endocrine organism. This causes us to feel hungry. Ghrelin
dissolves in water, but is completely repelled by fats. We know that blood is
hydrophilic, so the fact that Ghrelin is water soluble means that it can travel
through blood. Because Ghrelin is not fat soluble, it easily repels from fats
and other fatty structures. Ghrelin is a negative feedback loop, meaning that
the result of its process influences the operation of the process itself in
such a way as to reduce changes. Basically this means that the function slows
down when in contact with a stimulus. In the case of Ghrelin, it slows down our
hunger which allows us to live on without having to constantly eat. Thanks
and make sure you come back to hear me talk on my next podcast.
